PROMOTION

Tetrodotoxin, TTX Promotion!

Affix Scientific offers two different preparations of Puffer FishTetrodotoxin (TTx) Source: Natural, at the highest quality standard available and at an extremely attractive price!

*Cat. No: AF3015 Tetrodotoxin (with citrate) CAS No. 4368-28-9 – 1 mg / $110

*Cat. No: AF3014 Tetrodotoxin (citrate free) CAS No. 4368-28-9 – 1 mg / $110

  • Stable for months in lyophilized powder format.
  • Biological activity of each lot confirmed.
  • 24-48 hour delivery to most locations worldwide.

 

Tetrodotoxin is a potent and selective blocker of a subclass of Nav channels, and is often used to define subclasses of Nav channels.

References:

1.        Kao (1972) Pharmacology of tetrodotoxin and saxitoxin. Fed.Proc. 31 1117. PMID: 5032475.

2.        Catterall WA Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. Annu Rev Pharmacol Toxicol 20:15-43 (1980). Read more (PubMed: 6247957)

3.        Kao (1986) Structure-activity relations of tetrodotoxin, saxitoxin, and analogues. Ann.N.Y.Acad.Sci. 479 52. PMID: 2434008.

4.        Narahashi T et al. Recent advances in the study of mechanism of action of marine neurotoxins. Neurotoxicology 15:545-54 (1994). Read more (PubMed: 7854588)