6H05

CAS Number: 1469338-01-9


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Cat No.: 1469338-01-9
Biological Description:
6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).
IC50 value:
Target: K-Ras G12C
6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2].

Purity: >98%

Molecular formula: C20H30ClN3O2S3

Molecular Weight: 476.12

Storage Instructions: Two years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO

References: for more information, please visit http://www.ncbi.nlm.nih.gov