(-)-JQ-1

CAS Number: 1268524-71-5


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Cat No.: 1268524-71-5
Biological Description:
(-)-JQ-1, the stereoisomer (+)-JQ1, showed no significant interaction with any bromodomain; (+)-JQ1 is an inhibitor for the BET.
IC50 value:
Target: BET bromodomain
The ()-JQ1 stereoisomer has no appreciable affinity to BET bromodomains, whereas enantiomerically pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively.

Purity: >98%

Molecular formula: C23H25ClN4O2S

Molecular Weight: 456.99

Storage Instructions: Two years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO

References: for more information, please visit http://www.ncbi.nlm.nih.gov